University of California, Riverside

School of Medicine

Clinical Faculty Biographies

Dr. Xolani P. Mdluli

Health Sciences Assistant Clinical Professor - Internal Medicine

Dr. Xolani P. Mdluli

Medical Office

UCR Health Family Medicine Center
555 E. Tachevah Drive 2E-107
Palm Springs, Calif. 92262
(760) 561-7373

Academic Office

School of Medicine
University of California, Riverside
Riverside, Calif. 92521

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Contact the medical office by telephone.

Education and Training

  • Fellowship, Infectious Diseases, Stritch School of Medicine, Loyola University, Chicago, Illinois
  • Residency, Internal Medicine, Mt. Sinai School of Medicine/Jersey City Program, Jersey City Medical Center
  • M.D.,St. George's University, Grenada
  • B.S., Biology, Howard University, Washington D.C.


Dr. Xolani P. Mdluli, M.D., is an assistant clinical professor of internal medicine at the University of California, Riverside School of Medicine. He practices at the Desert Regional Medical Center in Palm Springs with an emphasis on infectious diseases and HIV medicine.

Mdluli previously was an attending infectious diseases specialist at Eisenhower Medical Center, where he initiated a comprehensive, interactive infectious disease resident rotation curriculum. He established the first HIV specialty clinic at Eisenhower Medical Center campus.

He conducted a fellowship in infectious diseases at Chicago's Loyola University Stritch School of Medicine. In addition to managing patients with a diverse spectrum of infectious diseases, he also taught and mentored residents and students rotating in infectious diseases.While at the San Joaquin Valley Pulmonary Medical Group, he was chief hospitalist.

After graduating Magna Cum Laude in biology from Howard University, Mdluli attended St. George's University in Grenada to earn his M.D. He conducted his residency at the Mt. Sinai School of Medicine/Jersey City Program (now known as the Icahn School of Medicine at Mount Sinai).

He is board certified in infectious disease and internal medicine and is fluent in English and SiSwati, the language of the Swazi people spoken in Swaziland and South Africa. He is a member of the Infectious Diseases Society of America, the American Association of HIV Medicine, the American Medical Association and the American College of Physicians.

Research Interests

Mdluli's interest in infectious diseases led him to create a standardized HIV template used to ensure continuity of care improve patient outcomes and operational efficiency. He also co-chaired the Ebola Preparedness Committee at Eisenhower Medical Center.

He has lectured on viral respiratory tract infections, Ebola, Chikungunya, empiric antimicrobial therapy, sepsis, and HIV/AIDS diagnosis and management.

He submitted an abstract titled" Use of Disinfection Caps on All Central Line Access Ports is Associated with Improved Patient Safety Through Substantial Reduction in CLABSI Rates, and Potential Substantial Savings in Healthcare Costs" for ID Week 2013.


  • Best Sub-Specialty Attending, Eisenhower Medical Center, 2013-14, 2014-15.
  • Graduating Fellow of the Year, Loyola University, Stritch School of Medicine, 2012-13.
  • Fellow Scholarship Award, Remington Winter Course in Infectious Diseases, 2013.
  • Bakersfield Memorial Hospital End of Life Care Discussion Award, 2008-9.
  • Mercy Hospital Dependability Award, 2008.
  • Certificate of Excellence for outstanding performance in the Cardiac Care Unit, 2007.
  • Press Ganey Patient Satisfaction Award, Jersey City Medical Center, 2006.

Selected Publications

  • Roberta D. De Keyser, M.D., Xolani P. Mdluli M.D., A Cheeky Situation: A Unique Case of Paratid Gland Coccidioidomycosis in a Healthy Individual from a Non-endemic Region. California-Hawaii Society of General Medicine. January, 2015.

More Information 

General Campus Information

University of California, Riverside
900 University Ave.
Riverside, CA 92521
Tel: (951) 827-1012

School Information

School of Medicine
2608 School of Medicine Education Building

Admissions Inquiries: (951) 827-7353

General Inquiries: (951) 827-4568

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