University of California, Riverside

School of Medicine



Faculty Biographies


Neal L. Schiller, Ph.D.

Professor Emeritus of Biomedical Sciences

Neal L. Schiller

University of California, Riverside
Riverside, CA 92521

Tel: (951) 827-4535
E-mail: neal.schiller@ucr.edu
Office: 2609 School of Medicine Education Building

Education and Training

  • Postdoc in infectious diseases, New York Hospital-Cornell Medical Center, 1976-78
  • Ph.D. Microbiology, University of Massachusetts, Amherst, 1976
  • B.S. Biology, Boston College

Research Summary

The study of the interaction of bacterial pathogens with human host defenses; analysis of the microbial physiology, genetics, immunobiology and pathogenesis of pseudomonas aeruginosa infection in cystic fibrosis patients; characterization of antibiotic resistance in helicobacter pylori; study of the antimicrobial activity of various cationic proteins.

Awards

  • Elected to UCR Academy of Distinguished Teachers, 2006-07.
  • Distinguished Teaching Award, University of California, Riverside, 2005-06.
  • Faculty Marshall at Hippocratic Oath Ceremony, UCLA, 1993 – awarded by graduating medical school class.

Selected Publications

  • Qureshi, N., D. Morikis, and N.L. Schiller. 2011. Contribution of Specific Amino Acid Changes in Penicillin Binding Protein-1 to Amoxicillin Resistance in Clinical Helicobacter pylori. Antimicrobial Agents & Chemotherapy 55: 101-109.
  • Clark, R.T., Hope, A., Lopez-Fraga, M., Schiller, N., Lo, D. 2009. Bacterial particle endocytosis by epithelial cells is selective and enhanced by tumor necrosis factor-receptor ligands. Clinical Vaccine Immunol 16: 397-407.
  • Cho, Y.S., Schiller, N.L., Oh, K.H. 2008. Antibacterial effects of green tea polyphenols on clinical isolates of methicillin-resistant Staphylococcus aureus. Curr. Microbiol. 57: 542-546.
  • Lee, J., L. Presley, E. Bent, J. Braun, N.L. Schiller, D. Straus, and J. Borneman. 2008. Bacteria and Bacterial rRNA Genes Associated with the Development of Colitis in IL-10-/- Mice. Inflammatory Bowel Disease 14: 1041-1050.
  • Cho, Y.-S., N.L. Schiller, H.-Y. Kahng and K.-Y. Oh. 2007. Cellular responses and proteomic analysis of Escherichia coli exposed to green tea polyphenols. Curr. Microbiol. 55: 501-506.
  • Co, E.-M. A. and N.L. Schiller. 2006. Resistance mechanisms in an in vitro-selected amoxicillin-resistant strain of Helicobacter pylori. Antimicrob. Agents Chemother. 50: 4174-4176.
  • Alkawash, M.A., J. S. Soothill, and N.L. Schiller. 2006. Alginate lyase enhances antibiotic killing of mucoid Pseudomonas aeruginosa in biofilms. APMIS 114: 131-138.
  • Albrecht, M.T. and N.L. Schiller. 2005. Alginate lyase (AlgL) activity is required for alginate biosynthesis in Pseudomonas aeruginosa. J. Bacteriol. 187: 3869-3872.
  • Robles-Price, A., T.Y. Wong, H. Sletta, S. Valla, and N.L. Schiller. 2004. AlgX is a periplasmic protein required for alginate biosynthesis in Pseudomonas aeruginosa. J. Bacteriol. 186: 7369-7377.
  • Albrecht, M.T., W. Wang, O. Shamova, R.I. Lehrer, and N.L. Schiller. 2002. Binding of protegrin-1 to Pseudomonas aeruginosa and Burkholderia cepacia. Respir. Res. 3: 18.
  • Preston, L.A., C.L. Bender and N.L. Schiller. 2001. Analysis and expression of <i>algL</i>, which encodes alginate lyase in Pseudomonas syringae pv. syringae. DNA Sequence 12: 455-461.
  • DeLoney, C.R. and N.L. Schiller. 2000. Characterization of an in-vitro selected amoxicillin-resistant strain of Helicobacter pylori. Antimicrob. Agents Chemother. 44: 3368-3373.
  • Preston, L.A., T-Y. Wong, C.L. Bender and N. L. Schiller. 2000. Characterization of alginate lyase from Pseudomonas syringae pv. syringae. J. Bacteriol. 182: 6268-6271.
  • Wong, T.Y., L.A. Preston, and N.L. Schiller. 2000. Alginate lyase: review of major sources and enzyme characteristics, structure-function analysis, biological roles, and applications. Annu. Rev. Microbiol. 54: 289-340.

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